Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL1 All Species: 18.79
Human Site: S650 Identified Species: 34.44
UniProt: P28749 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28749 NP_002886.2 1068 120847 S650 S V H E R Y S S P T A G S A K
Chimpanzee Pan troglodytes XP_001139919 1068 120960 S650 S V H E R Y S S P T A G S A K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534412 1068 120563 S650 S V H E R Y S S P T A G S A K
Cat Felis silvestris
Mouse Mus musculus Q64701 1063 119481 S650 S V H E R Y S S P A A G S A K
Rat Rattus norvegicus O55081 1135 127799 S682 T R R R L F E S D S P S E G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 A630 N D G P S D A A P P S R A P S
Chicken Gallus gallus Q90600 921 104417 I528 Y K V I E S F I K V E P S L T
Frog Xenopus laevis NP_001084880 998 113114 G603 R Y S S P A A G S A K R R L F
Zebra Danio Brachydanio rerio NP_001124082 1058 120023 S651 S L H D R Y S S P A A G S A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 Q452 Y L L D Q I L Q A E I R N K P
Honey Bee Apis mellifera XP_395096 1006 113492 A609 Q P V L R R I A L D R G T H H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q3LXA7 1010 111475 E597 K R H L N S L E E R L L E S M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 E598 L L E S M V W E K G S S M Y N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 95 N.A. 90.3 48.9 N.A. 52.8 22.1 63.9 63.2 N.A. 25.4 43.1 N.A. N.A.
Protein Similarity: 100 99.8 N.A. 98 N.A. 95.6 65.9 N.A. 69.7 37.8 77.3 77 N.A. 44.4 63.2 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 6.6 N.A. 6.6 6.6 0 80 N.A. 0 13.3 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 26.6 N.A. 40 6.6 6.6 93.3 N.A. 26.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. 25 N.A. 22.4 N.A. N.A.
Protein Similarity: N.A. 43.9 N.A. 42 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 16 16 8 24 39 0 8 39 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 16 0 8 0 0 8 8 0 0 0 0 0 % D
% Glu: 0 0 8 31 8 0 8 16 8 8 8 0 16 0 0 % E
% Phe: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 8 0 0 0 0 8 0 8 0 47 0 8 0 % G
% His: 0 0 47 0 0 0 0 0 0 0 0 0 0 8 8 % H
% Ile: 0 0 0 8 0 8 8 8 0 0 8 0 0 0 0 % I
% Lys: 8 8 0 0 0 0 0 0 16 0 8 0 0 8 39 % K
% Leu: 8 24 8 16 8 0 16 0 8 0 8 8 0 16 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 8 % M
% Asn: 8 0 0 0 8 0 0 0 0 0 0 0 8 0 8 % N
% Pro: 0 8 0 8 8 0 0 0 47 8 8 8 0 8 8 % P
% Gln: 8 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 16 8 8 47 8 0 0 0 8 8 24 8 0 0 % R
% Ser: 39 0 8 16 8 16 39 47 8 8 16 16 47 8 16 % S
% Thr: 8 0 0 0 0 0 0 0 0 24 0 0 8 0 8 % T
% Val: 0 31 16 0 0 8 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 16 8 0 0 0 39 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _